Platelets facilitate the wound-healing capability of mesenchymal stem cells by mitochondrial transfer and metabolic reprogramming
نویسندگان
چکیده
Main Text(Cell Metabolism 33, 283–299.e1–e9; February 2, 2021)Figure 3G. Platelet-Derived Mitochondria Stimulate Pro-angiogenic Properties of MSCs (original)View Large Image Figure ViewerDownload Hi-res image Download (PPT)Figure 5C. Angiogenesis via Activation De Novo Fatty Acid Synthesis in (corrected)View 7F. Citrate Restores the Effects Incubated with ROT/AA-Treated Platelets (PPT) (Cell 2021) Facilitate Wound-Healing Capability Mesenchymal Stem Cells by Mitochondrial Transfer and Metabolic ReprogrammingLevoux et al.Cell MetabolismJanuary 4, 2021In BriefLevoux al., report a novel mechanism which platelets improve regenerative capacity mesenchymal stem cells (MSCs). They discovered that activated release respiratory-competent mitochondria to this process improves MSC pro-angiogenic function through elevation cytosolic citrate level stimulation fatty acid synthesis. Full-Text PDF Open Archive
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ژورنال
عنوان ژورنال: Cell Metabolism
سال: 2021
ISSN: ['1550-4131', '1932-7420']
DOI: https://doi.org/10.1016/j.cmet.2021.02.003